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Wilson Disease

Also called: Copper storage disease, Hepatolenticular degeneration
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Summary

Wilson disease is a rare inherited disorder that prevents your body from getting rid of extra copper. You need a small amount of copper from food to stay healthy. Too much copper is poisonous.

Normally, your liver releases extra copper into bile, a digestive fluid. With Wilson disease, the copper builds up in your liver, and it releases the copper directly into your bloodstream. This can cause damage to your brain, kidneys, and eyes.

Wilson disease is present at birth, but symptoms usually start between ages 5 and 35. It first attacks the liver, the central nervous system or both. The most characteristic sign is a rusty brown ring around the cornea of the eye. A physical exam and laboratory tests can diagnose it.

Treatment is with drugs to remove the extra copper from your body. You need to take medicine and follow a low-copper diet for the rest of your life. Don't eat shellfish or liver, as these foods may contain high levels of copper. At the beginning of treatment, you'll also need to avoid chocolate, mushrooms, and nuts. Have your drinking water checked for copper content and don't take multivitamins that contain copper.

With early detection and proper treatment, you can enjoy good health.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Start Here

  • From the National Institutes of Health (National Institute of Diabetes and Digestive and Kidney Diseases)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (Wilson's Disease Association)
  • (Mayo Foundation for Medical Education and Research) Also in

Diagnosis and Tests

  • (American Association for Clinical Chemistry)
  • (Wilson's Disease Association)
  • (Wilson's Disease Association)

Living With

  • (Wilson's Disease Association)
  • (Wilson's Disease Association)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • (Wilson's Disease Association)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • (American College of Gastroenterology)
  • From the National Institutes of Health
  • From the National Institutes of Health Also in

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