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Sjogren's Syndrome

Summary

Sjogren's syndrome is an autoimmune disease. This means that your immune system attacks parts of your own body by mistake. In Sjogren's syndrome, it attacks the glands that make tears and saliva. This causes a dry mouth and dry eyes. You may have dryness in other places that need moisture, such as your nose, throat, and skin. Sjogren's can also affect other parts of the body, including your joints, lungs, kidneys, blood vessels, digestive organs, and nerves.

Most people with Sjogren's syndrome are women. It usually starts after age 40. It is sometimes linked to other diseases such as rheumatoid arthritis and lupus.

To make a diagnosis, doctors may use a medical history, physical exam, certain eye and mouth tests, blood tests, and biopsies.

Treatment focuses on relieving symptoms. It can differ for each person; it depends on what parts of the body are affected. It may include artificial tears for dye eyes and sucking on sugar-free candy or drinking water often for a dry mouth. Medicines may help with severe symptoms.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Start Here

  • From the National Institutes of Health (National Institutes of Health)
  • (Mayo Foundation for Medical Education and Research)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (American College of Rheumatology)
  • From the National Institutes of Health Easy-to-Read (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Diagnosis and Tests

  • (American Association for Clinical Chemistry)
  • (American College of Rheumatology) Also in
  • (American Association for Clinical Chemistry)

Treatments and Therapies

  • (Sjogren's Syndrome Foundation) - PDF

Living With

  • (Sjogren's Syndrome Foundation) - PDF
  • (Sjogren's Syndrome Foundation) - PDF
  • (Sjogren's Syndrome Foundation) - PDF

Related Issues

  • (Mayo Foundation for Medical Education and Research)
  • (Sjogren's Syndrome Foundation) - PDF
  • (Sjogren's Syndrome Foundation) - PDF
  • (Sjogren's Syndrome Foundation) - PDF
  • (Lupus Foundation of America)

Specifics

Genetics

  • From the National Institutes of Health (National Library of Medicine)

Videos and Tutorials

  • Video (Sjogren's Syndrome Foundation)

Statistics and Research

  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • (American College of Rheumatology)
  • From the National Institutes of Health Also in
  • From the National Institutes of Health Also in
  • From the National Institutes of Health Also in

Patient Handouts

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