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Pemphigus

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Summary

Pemphigus is an autoimmune disorder. If you have it, your immune system attacks healthy cells in your skin and mouth, causing blisters and sores. No one knows the cause. Pemphigus does not spread from person to person. It does not appear to be inherited. But some people's genes put them more at risk for pemphigus.

Pemphigoid is also an autoimmune skin disease. It leads to deep blisters that do not break easily. Pemphigoid is most common in older adults and may be fatal for older, sick patients.

Doctors diagnose pemphigus with a physical exam, a biopsy, and blood tests. The treatment of pemphigus and pemphigoid is the same: one or more medicines to control symptoms. These may include

  • Steroids, which reduce inflammation
  • Drugs that suppress the immune system response
  • Antibiotics to treat associated infections

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

Start Here

  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Specifics

  • (American Osteopathic College of Dermatology)
  • (American Academy of Oral & Maxillofacial Pathology) - PDF
  • (American Osteopathic College of Dermatology)

Genetics

  • From the National Institutes of Health (National Library of Medicine)

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Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • (American Academy of Dermatology)
  • From the National Institutes of Health Also in

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