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Paget's Disease of Bone

Also called: Osteitis deformans
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Summary

Paget's disease of bone causes your bones to grow too large and weak. They also might break easily. The disease can lead to other health problems, too, such as arthritis and hearing loss. You can have Paget's disease in any bone, but it is most common in the spine, pelvis, skull, and legs. The disease might affect one or several bones, but not your entire skeleton. More men than women have the disease. It is most common in older people.

No one knows what causes Paget's disease. In some cases, a virus might be responsible. It tends to run in families. Many people do not know they have Paget's disease because their symptoms are mild. For others, symptoms can include

  • Pain
  • Enlarged bones
  • Broken bones
  • Damaged cartilage in joints

Doctors use blood tests and imaging tests to diagnose Paget's disease. Early diagnosis and treatment can prevent some symptoms from getting worse. Treatments include medicines and sometimes surgery. A good diet and exercise might also help.

NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases

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  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
  • From the National Institutes of Health Easy-to-Read (National Institute of Arthritis and Musculoskeletal and Skin Diseases) Also in

Diagnosis and Tests

  • Alkaline Phosphatase From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • (American Association for Clinical Chemistry)
  • (Mayo Foundation for Medical Education and Research) Also in
  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Related Issues

  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • (American College of Rheumatology)
  • (Hormone Health Network)
  • From the National Institutes of Health Also in
  • From the National Institutes of Health (National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Patient Handouts

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