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Myelodysplastic Syndromes

Also called: MDS

Summary

Your bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains immature cells, called stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting. If you have a myelodysplastic syndrome, the stem cells do not mature into healthy blood cells. Many of them die in the bone marrow. This means that you do not have enough healthy cells, which can lead to infection, anemia, or easy bleeding.

Myelodysplastic syndromes often do not cause early symptoms and are sometimes found during a routine blood test. If you have symptoms, they may include

  • Shortness of breath
  • Weakness or feeling tired
  • Skin that is paler than usual
  • Easy bruising or bleeding
  • Pinpoint spots under the skin caused by bleeding
  • Fever or frequent infections

Myelodysplastic syndromes are rare. People at higher risk are over 60, have had chemotherapy or radiation therapy, or have been exposed to certain chemicals. Treatment options include transfusions, drug therapy, chemotherapy, and blood or bone marrow stem cell transplants.

NIH: National Cancer Institute

Start Here

  • From the National Institutes of Health (National Cancer Institute)
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Diagnosis and Tests

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Prevention and Risk Factors

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Treatments and Therapies

Related Issues

  • From the National Institutes of Health (National Institute of Diabetes and Digestive and Kidney Diseases)
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Specifics

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Genetics

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  • From the National Institutes of Health (National Library of Medicine)
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Statistics and Research

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Clinical Trials

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Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

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Children

  • (Leukemia & Lymphoma Society)

Patient Handouts

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