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Leukodystrophies

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Summary

The leukodystrophies are rare diseases that affect the cells of the brain. Specifically, the diseases affect the myelin sheath, the material that surrounds and protects nerve cells. Damage to this sheath slows down or blocks messages between the brain and the rest of the body. This leads to problems with

  • Movement
  • Speaking
  • Vision
  • Hearing
  • Mental and physical development

Most of the leukodystrophies are genetic. They usually appear during infancy or childhood. They can be hard to detect early because children seem healthy at first. However, symptoms gradually get worse over time.

There are no cures for any of the leukodystrophies. Medicines, speech therapy and physical therapy might help with symptoms. Researchers are testing bone marrow transplantation as a treatment for some of the leukodystrophies.

NIH: National Institute of Neurological Disorders and Stroke

Start Here

  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke) Also in
  • (United Leukodystrophy Foundation)

Treatments and Therapies

  • (National Marrow Donor Program)
  • (National Marrow Donor Program)

Specifics

  • (United Leukodystrophy Foundation)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (National Marrow Donor Program)
  • (United Leukodystrophy Foundation)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (United Leukodystrophy Foundation)
  • (United Leukodystrophy Foundation)
  • (Mayo Foundation for Medical Education and Research)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (United Leukodystrophy Foundation)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (United Leukodystrophy Foundation)
  • (United Leukodystrophy Foundation)
  • (United Leukodystrophy Foundation)
  • (United Leukodystrophy Foundation)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • From the National Institutes of Health
  • From the National Institutes of Health Also in
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