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Bilirubin Blood Test

What is a Bilirubin Blood Test?

A bilirubin blood test measures the levels of bilirubin in your blood. Bilirubin is a yellowish substance made during the body's normal process of breaking down red blood cells. Bilirubin is found in bile, a fluid in your liver that helps you digest food. If your liver is healthy, it will remove most of the bilirubin from your body. If your liver is damaged, bilirubin can leak out of your liver and into your blood. When too much bilirubin gets into the bloodstream, it can cause jaundice, a condition that causes your skin and eyes to turn yellow. Signs of jaundice, along with a bilirubin blood test, can help your health care provider find out if you have liver disease.

Other names: Total serum bilirubin, TSB

What is it used for?

A bilirubin blood test is used to check the health of your liver. The test is also commonly used to help diagnose newborn jaundice. Many healthy babies get jaundice because their livers aren't mature enough to get rid of enough bilirubin. Newborn jaundice is usually harmless and clears up within a few weeks. But in some cases, high bilirubin levels can lead to brain damage, so infants are often tested as a precaution.

Why do I need a bilirubin blood test?

Your health care provider may order a bilirubin blood test:

  • If you have symptoms such as jaundice, dark urine, or stomach pain. These could indicate hepatitis, cirrhosis, or other liver diseases
  • To find out if there is a blockage in the structures that carry bile from your liver
  • To monitor an existing liver disease or disorder
  • To diagnose disorders related to problems with red blood cell production. High bilirubin levels in the bloodstream may be a sign of gallbladder disease and a condition called hemolytic anemia

What happens during a bilirubin blood test?

A health care professional will take a blood sample from a vein in your arm, using a small needle. After the needle is inserted, a small amount of blood will be collected into a test tube or vial. You may feel a little sting when the needle goes in or out. This usually takes less than five minutes.

Will I need to do anything to prepare for the test?

You don't need any special preparations for a bilirubin blood test. If your health care provider has also ordered other blood tests, you may need to fast (not eat or drink) for several hours before the test. Your health care provider will let you know if there are any special instructions to follow.

Are there any risks to the test?

There is very little risk to having a blood test. You may have slight pain or bruising at the spot where the needle was put in, but most symptoms go away quickly.

What do the results mean?

Normal results can vary, but high bilirubin levels can mean your liver isn't working right. However, abnormal results don't always indicate a medical condition needing treatment. Higher than normal bilirubin levels can also be caused by medications, certain foods, or strenuous exercise. To learn what your results mean, talk to your health care provider.

Is there anything else I need to know about a bilirubin blood test?

A bilirubin blood test is only one measure of your liver health. If your health care provider thinks you might have a liver disease or a red blood cell disorder, other tests may be recommended. These include liver function tests, a group of tests that measure different substances in your blood, and tests for certain proteins made in the liver. In addition, your health care provider may recommend urine tests, an ultrasound, or a biopsy to get a sample of tissue from your liver to examine

References

  1. American Liver Foundation. [Internet]. New York: American Liver Foundation; c2017. Liver Function Tests; [updated 2016 Jan 25; cited 2017 Jan 31]; [about 4 screens]. Available from:
  2. Healthy Children.org. [Internet]. Elk Grove Village (IL): American Academy of Pediatrics; c2017. Jaundice in Newborns Q&A; 2009 Jan 1 [cited 2017 Jan 31]; [about 3 screens]. Available from:
  3. Lab Tests Online [Internet]. Washington D.C.: American Association for Clinical Chemistry; c2001–2017. Bilirubin; [updated 2015 Dec 16; cited 2017 Jan 31]; [about 3 screens]. Available from:
  4. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2017. Bilirubin test: Definition; 2016 Jul 2 [cited 2017 Jan 31]; [about 2 screens]. Available from:
  5. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2017. Bilirubin test: Results; 2016 Jul 2 [cited 2017 Jan 31]; [about 6 screens]. Available from:
  6. Mayo Clinic [Internet]. Mayo Foundation for Medical Education and Research; c1998-2017. Bilirubin test: Why it's done; 2015 Oct 13 [cited 2017 Jan 31]; [about 4 screens]. Available from:
  7. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; How Is Hemolytic Anemia Diagnosed? [updated 2014 Mar 21; cited 2017 Jan 31]; [about 5 screens]. Available from:
  8. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; What Are the Risks of Blood Tests? [updated 2012 Jan 6; cited 2017 Jan 31]; [about 5 screens]. Available from:
  9. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; What To Expect with Blood Tests; [updated 2012 Jan 6; cited 2017 Jan 31]; [about 5 screens]. Available from:
  10. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; What Do Blood Tests Show? [updated 2012 Jan 6; cited 2017 Jan 31]; [about 5 screens]. Available from:
  11. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; c2017. Health Encyclopedia: Total Bilirubin (Blood); [cited 2017 Jan 31]; [about 3 screens]. Available from:

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The medical information provided is for informational purposes only, and is not to be used as a substitute for professional medical advice, diagnosis or treatment. Please contact your health care provider with questions you may have regarding medical conditions or the interpretation of test results.

In the event of a medical emergency, call 911 immediately.
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