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Down Syndrome

Also called: Trisomy 21

Summary

Down syndrome is a condition in which a person is born with an extra copy of chromosome 21. People with Down syndrome can have physical problems, as well as intellectual disabilities. Every person born with Down syndrome is different.

People with the syndrome may also have other health problems. They may be born with heart disease. They may have dementia. They may have hearing problems and problems with the intestines, eyes, thyroid, and skeleton.

The chance of having a baby with Down syndrome increases as a woman gets older. Down syndrome cannot be cured. Early treatment programs can help improve skills. They may include speech, physical, occupational, and/or educational therapy. With support and treatment, many people with Down syndrome live happy, productive lives.

NIH: National Institute of Child Health and Human Development

Start Here

  • (Nemours Foundation) Also in
  • (American Academy of Family Physicians)
  • (Centers for Disease Control and Prevention) Also in
  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Symptoms

  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in

Diagnosis and Tests

  • Alpha-fetoprotein (AFP) Test From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in
  • (American College of Nurse-Midwives) - PDF

Treatments and Therapies

  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in

Related Issues

  • From the National Institutes of Health (National Institute on Aging)
  • (National Down Syndrome Society)
  • (National Down Syndrome Society)
  • (American Association for Pediatric Ophthalmology and Strabismus) Also in
  • (National Down Syndrome Society)
  • (National Down Syndrome Society)
  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in
  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in
  • (National Down Syndrome Society)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Human Genome Research Institute)

Statistics and Research

  • From the National Institutes of Health (National Institute of Child Health and Human Development)
  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Find an Expert

  • Also in
  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in
  • Also in

Children

  • (Nemours Foundation) Also in

Seniors

  • (Alzheimer's Association)

Patient Handouts

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