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Cushing's Syndrome

Also called: Hypercortisolism

Summary

Cushing's syndrome is a hormonal disorder. The cause is long-term exposure to too much cortisol, a hormone that your adrenal gland makes. Sometimes, taking synthetic hormone medicine to treat an inflammatory disease leads to Cushing's. Some kinds of tumors produce a hormone that can cause your body to make too much cortisol.

Cushing's syndrome is rare. Some symptoms are

  • Upper body obesity
  • Thin arms and legs
  • Severe fatigue and muscle weakness
  • High blood pressure
  • High blood sugar
  • Easy bruising

Lab tests can show if you have it and find the cause. Your treatment will depend on why you have too much cortisol. If it is because you have been taking synthetic hormones, a lower dose may control your symptoms. If the cause is a tumor, surgery and other therapies may be needed.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases

Start Here

  • (American Academy of Family Physicians) Also in
  • From the National Institutes of Health (National Institute of Diabetes and Digestive and Kidney Diseases)
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)

Symptoms

  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Diagnosis and Tests

  • (American Association for Clinical Chemistry)
  • Cortisol Test From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Treatments and Therapies

  • From the National Institutes of Health (National Institute of Child Health and Human Development)
  • (Cushing's Support and Research Foundation)
  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Related Issues

  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Specifics

  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)

Statistics and Research

  • From the National Institutes of Health (National Institute of Child Health and Human Development)
  • From the National Institutes of Health (National Institute of Child Health and Human Development)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Reference Desk

  • (Nemours Foundation) Also in

Find an Expert

  • From the National Institutes of Health (National Institute of Child Health and Human Development) Also in
  • (Hormone Health Network)
  • From the National Institutes of Health

Children

  • (Cushing's Support and Research Foundation) - PDF

Patient Handouts

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