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Bone Marrow Diseases

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Summary

Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.

With bone marrow disease, there are problems with the stem cells or how they develop:

  • In leukemia, a cancer of the blood, the bone marrow makes abnormal white blood cells
  • In aplastic anemia, the bone marrow doesn't make red blood cells
  • In myeloproliferative disorders, the bone marrow makes too many white blood cells
  • Other diseases, such as lymphoma, can spread into the bone marrow and affect the production of blood cells

Causes of bone marrow diseases include genetics and environmental factors. Tests for bone marrow diseases include blood and bone marrow tests. Treatments depend on the disorder and how severe it is. They might involve medicines, blood transfusions or a bone marrow transplant.

Symptoms

  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)

Diagnosis and Tests

  • Blood Count Tests: FreeFacebookCredits2012 Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • (American Association for Clinical Chemistry)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • (American Association for Clinical Chemistry)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)

Treatments and Therapies

  • Bone Marrow Transplantation: FreeFacebookCredits2012 Health Topic From the National Institutes of Health (National Library of Medicine) Also in Spanish
  • From the National Institutes of Health (National Cancer Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in

Living With

  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)

Specifics

  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute)
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Cancer Institute) Also in
  • (Mayo Foundation for Medical Education and Research)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)
  • From the National Institutes of Health (National Heart, Lung, and Blood Institute)

Genetics

  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)
  • From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)
  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

Reference Desk

  • From the National Institutes of Health (National Cancer Institute)

Find an Expert

  • From the National Institutes of Health Also in
  • From the National Institutes of Health

Patient Handouts

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