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Ataxia Telangiectasia

Summary

Ataxia-telangiectasia (A-T) is a rare, inherited disease. It affects the nervous system, immune system, and other body systems. Symptoms appear in young children, usually before age 5. They include

  • Ataxia - trouble coordinating movements
  • Poor balance
  • Slurred speech
  • Tiny, red spider veins, called telangiectasias, on the skin and eyes
  • Lung infections
  • Delayed physical and sexual development

People with A-T have an increased risk of developing diabetes and cancers, especially lymphoma and leukemia. Although it affects the brain, people with A-T usually have normal or high intelligence.

A-T has no cure. Treatments might improve some symptoms. They include injections to strengthen the immune system, physical and speech therapy, and high-dose vitamins.

NIH: National Institute of Neurological Disorders and Stroke

Resources

  • Ataxia - telangiectasia (Medical Encyclopedia) Also in Spanish
  • From the National Institutes of Health (National Cancer Institute) Also in
  • From the National Institutes of Health (National Institute of Neurological Disorders and Stroke)
  • (American Academy of Neurology)
  • From the National Institutes of Health Also in
  • (Ataxia-Telangiectasia Children's Project)

Genetics

  • From the National Institutes of Health (National Library of Medicine)

Clinical Trials

  • From the National Institutes of Health (National Institutes of Health)

Journal Articles References and abstracts from MEDLINE/PubMed (National Library of Medicine)

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